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Laboratories 

SYNTHON has 400m2 of well-equipped laboratories for research and development purposes and small-scale production as well. These laboratories are designed to be used for many physical and chemical operations, in order to develop new procedures, to optimise existing processes and to scale up multi step procedures.

 Kilo-Lab

 SYNTHON has 2 kilo labs with multi-purpose equipment for process development and for production of fine chemicals and specialities for electronic, diagnostic and pharmaceutical applications.

Reactors:

Material

Number

Volume

Equipped with

Glass lined (1)

2

100l

Stirrer, supply tank, reflux condenser, distillation,
water separator

Glass

2

60l

stirrer, dropping funnel, reflux condenser

Glass

1

25l

stirrer, dropping funnel, reflux condenser

Glass

3

25l

stirrer, dropping funnel, reflux condenser

Double jacket glass

1

30l

multi purpose reactor with stirrer, dropping funnel,
reflux condenser, distillation column, water separator

Double jacket glass

1

25l

stirrer, dropping funnel, reflux condenser,
reflux separator for distillation

Double jacket glass

1

50 l (spherical)

stirrer, dropping funnel, reflux condenser

(1) Initial startup 3rd quarter 2007.

Autoclaves:

Material

Number

Volume

Temperature / Pressure

Hastelloy (2)

1

60l

250°C/100 bar

Hastelloy

1

3,75l

300 °C/200 bar

Stainless steel, teflon coated

1

3,75l

300 °C/200 bar

Glass

1

3,00l

-20°C - 100°C/ 14 bar

(2) Initial startup 3rd quarter 2007.

 

6 Thermostats:  -50 °C to 200 °C (Lauda and Haake)

Rotary evaporators: 2 x 20 l (Heidolph) 1x 10 l (Bόchi)

Distillation/Rectification equipment:
6 l automatic vacuum distillation apparatus (Fischer), Sulzer packing, 100 theoretical plates

Columns for chromatography: Up to 20 cm diameter, 100 cm long

Absorbers, Filters, Dryers, Mills

Filling and bottling department for dangerous goods:
• 2 Denios hoods for filling of bottles up to 2.5 l
• 1 Denios hood (practicable) for filling and repacking of drums

Warehouses for dangerous and nondangerous goods: 200 m2
 

Outsourcing / Cooperation partners: 

• Orgentis GmbH (reactors from 50 to 250 l)
• Organica Feinchemie GmbH (reactors from 100 to 4000 l)

Analytical Test Methods (from subcontractors):

• HPLC    
• GC, GC-MS
• NMR (1H-, 13C-, 19F-, 31P-)           
• AAS / ICP
• FT-IR, Fourier-Transform
• DSC
• UV/VIS spectroscopy
• Fluorescence spectrometry
• Loss on drying
• Titration (automatically)
• Water-titration (Karl-Fischer)           
• Density measurements

 

 

(C) 2010 SYNTHON Chemicals GmbH & Co. KG